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Data for the paper: "Positive interactions of mechanical loading and PTH treatments on spatio-temporal bone remodelling"

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posted on 2021-09-27, 14:21 authored by Enrico Dall'AraEnrico Dall'Ara, Vee San CheongVee San Cheong
Data used in the paper : "Bone remodelling in the mouse tibia is spatio-temporally modulated by oestrogen deficiency and external mechanical loading: a combined in vivo/ in silico study"<div><br></div><div>by</div><div><div>VS Cheong, BC Roberts, V Kadirkamanathan, E Dall'Ara (2021)</div><div>published in Acta Biomaterialia<br></div></div><div><br></div><div><br></div><div>We share here an example of in vivo microCT images collected for a mouse that underwent the following interventions:</div><div>-ovariectomy at week 14 of age </div><div>- mechanical loading at week 19 and 21 of age.</div><div>- injections of Parathyroid hormone (PTH; 5 days per week) between weeks 18 and 22 of age</div><div><br></div><div>In vivo 3D microCT images of the mouse tibia have been acquired at week 14, 18, 20, and 22 of age.</div><div>The registered and cropped images are reported here.</div><div><br></div><div>In case the reader is interested in the whole database they should contact Dr Enrico Dall'Ara (e.dallara@sheffield.ac.uk).</div>

Funding

This work was supported by funding from the Engineering and Physical Sciences Research Council (EPSRC) Frontier Multisim Grant (EP/K03877X/1 and EP/S032940/1) and the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs; NC/R001073/1).

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    Department of Mechanical Engineering

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