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Multiscale topological analysis of kinetoplast DNA via high-resolution AFM

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posted on 2024-09-06, 00:20 authored by Sylvia WhittleSylvia Whittle, Bradley Diggines, Thomas CatleyThomas Catley, Indresh Yadav, Elizabeth HolmesElizabeth Holmes, Daniel RollinsDaniel Rollins, Patrick S. Doyle, Alice PyneAlice Pyne

High-resolution atomic force microscopy of single kinetoplast DNA molecules reveals structural heterogeneity and complex catenation behaviour across several length scales.

Data analysis is described in the accompanying publication.

Funding

Unravelling the invisible complexities of the genome

UK Research and Innovation

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