posted on 2024-04-16, 15:48authored byLucy Urwin, Peter N. Monk
Supplementary data from the PhD thesis, 'The Development of in vitro Corneal Infection Models for Antimicrobial Drug Testing' (Lucy Urwin, 2022, Dept. IICD).
Chapter 4 of the thesis describes characterisation of clinical isolates, including 39 Pseudomonas aeruginosa isolates from LV Prasad Eye Institute, Hyderabad, India. Genome sequencing was performed by Microbes NG (LVP3-6), Dr Luke Green, University of Sheffield (LVP3-6) and Dr Naveen Kumar, Christian Medical College, Vellore (all other isolates).
FASTA files were analysed using the Comprehensive Antibiotic Resistance Database Resistance Gene Identifier (CARD-RGI). This file contains details of perfect and strict hits for antibiotic resistance genes, as identified by CARD-RGI.
See README file for more details.
Funding
Adhesion to host cell membrane microdomains in cornea as an antimicrobial target to prevent corneal ulceration