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.CEL
1_C-SNB 20961_(Clariom_S_Human).CEL (2.91 MB)
.CHP
1_C-SNB 20961_(Clariom_S_Human).rma-gene-full.chp (1.04 MB)
.CEL
2_C-SNB 20961_(Clariom_S_Human).CEL (2.9 MB)
.CHP
2_C-SNB 20961_(Clariom_S_Human).rma-gene-full.chp (1.04 MB)
.CEL
3_C-SNB 14743_(Clariom_S_Human).CEL (2.9 MB)
.CHP
3_C-SNB 14743_(Clariom_S_Human).rma-gene-full.chp (1.04 MB)
.CEL
7_SNB 21481_(Clariom_S_Human).CEL (2.9 MB)
.CHP
7_SNB 21481_(Clariom_S_Human).rma-gene-full.chp (1.04 MB)
.CEL
8_SNB 21481_(Clariom_S_Human).CEL (2.9 MB)
.CHP
8_SNB 21481_(Clariom_S_Human).rma-gene-full.chp (1.04 MB)
.CEL
9_SNB 21481_(Clariom_S_Human).CEL (2.9 MB)
.CHP
9_SNB 21481_(Clariom_S_Human).rma-gene-full.chp (1.04 MB)
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12 files

Microarray data for "MYT1L mutations cause intellectual disability and variable obesity by dysregulating gene expression and development of the neuroendocrine hypothalamus"

Version 2 2021-04-20, 19:41
Version 1 2017-08-18, 13:16
dataset
posted on 2021-04-20, 19:41 authored by Alisdair McNeillAlisdair McNeill
Organism: Human Embryonic (HEK) line
samples: 3 x CRISPR Knockout HEK line cultures and 3x isogenic wild type HEK cell cultures
Array: Clarion S array (Thermofisher)
Experiment: whole genome gene expression profiling in MYT1L null HEK cell lines (generated by CRISPR) and 3 x isogenic wild type HEK cell lines.

Protocol provided in "MYT1L mutations cause intellectual disability and variable obesity by dysregulating gene expression and development of the neuroendocrine hypothalamus" Published in PLoS Genetics, 13 (8). e1006957. ISSN 1553-7390 DOI: 10.1371/journal.pgen.1006957


"C" files are from isogenic controls.
"21481" files are from MYT1L null cells

Funding

BDF Newlife SG/15-16/07

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  • There is no personal data or any that requires ethical approval

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  • The data complies with the institution and funders' policies on access and sharing

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  • The data can be shared openly

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  • The file formats are open or commonly used

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  • Headings and units are explained in the files

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    Department of Neuroscience

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