Cell population growth models

Schematic representation of cell population in discrete models, where cells are represented in pink with nucleus in red. (A) On-lattice approach: squared 2D lattice where each lattice element contains one single cell. At the top right void locations are free to be occupied by daughter cells. (B) Cellular Potts model: squared lattice where each cell occupies several lattice elements. Cells are represented with different colors. (C) Compartmental model 2D: similar to squared lattice but having several cells per lattice element. (D) Off-lattice agent based approach in 3D: cells are represented by spheres and are not constrained in a lattice. (E) Off-lattice Vertex based 2D: cell surface delimited by polyhedral vertices of a Voronoi tessellation.