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Cell population growth models

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posted on 2016-02-10, 13:09 authored by Daniele Tartarini, Elisa MeleElisa Mele
Schematic representation of cell population in discrete models, where cells are represented in pink with nucleus in red. (A) On-lattice approach: squared 2D lattice where each lattice element contains one single cell. At the top right void locations are free to be occupied by daughter cells. (B) Cellular Potts model: squared lattice where each cell occupies several lattice elements. Cells are represented with different colors. (C) Compartmental model 2D: similar to squared lattice but having several cells per lattice element. (D) Off-lattice agent based approach in 3D: cells are represented by spheres and are not constrained in a lattice. (E) Off-lattice Vertex based 2D: cell surface delimited by polyhedral vertices of a Voronoi tessellation.
The figure is generated using Inkscape open source program (www.inkscape.org)

Funding

“Accelerating in silico cancer research with graphic processors” of the Engineering and Physical Science Research Council, EPSRC grant code R/141365-11-1

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