Eliciting societal preferences for burden of illness, therapeutic improvement and end of life for value based pricing: A report of the main survey

This report presents the findings of a study to elicit societal references for quality adjusted life year (QALY) gains from health care interventions. The aim was to elicit societal preferences across three characteristics: (1) burden of illness (BOI) from a medical condition given current health care interventions (i.e. QALY loss per patient from a condition due to both premature mortality measured against normal life expectancy and health related quality of life (HRQoL) below one), (2) therapeutic
improvement (TI) (i.e. whether preferences for large QALY gains are disproportionately larger than the size of the gain), and (3) end of life (EOL) (defined by the National Institute for Health and Care Excellence (NICE) to be expected survival of less than 2 years and expected survival gain of 3 months or more, though survival is also examined as a continuous variable).