Neil Shephard

Publications

• Derivation and validation of a risk adjustment model for predicting seven day mortality in emergency medical admissions: mixed prospective and retrospective cohort study
• The HubBLe trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for haemorrhoids
• The HubBLe trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for haemorrhoids.
• A breast cancer risk haplotype in the caspase-8 gene
• Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis
• Genome wide association analysis of juvenile idiopathic arthritis (JIA) identifies a novel JIA susceptibility locus
• Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs
• Linkage analysis of cross-sectional and longitudinally derived phenotypic measures to identify loci influencing blood pressure
• Association of rheumatoid arthritis (RA) to programmed cell death 2 (PDCD2), a potential autoimmune gene.
• Angiotensinogen gene T235 variant: a marker for the development of persistent microalbuminuria in children and adolescents with type 1 diabetes mellitus
• Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes
• Identification of CASP8 haplotypes associated with breast cancer using haploConstructor
• Multicentre study of CASP8 polymorphisms in breast cancer
• A whole genome by association of chronic inflammatory arthritis
• Association between osteopontin and human abdominal aortic aneurysm
• Fine mapping of genes within the IDDM8 region in rheumatoid arthritis
• Linkage analysis of rheumatoid arthritis in US and UK families reveals interactions between HLA--DRB1 and loci on chromosomes 6q and 16p
• Will the real disease gene please stand up?
• ANALYSIS OF COMBINED US-UK RA WGS IDENTIFIES A SUSCEPTIBILITY LOCUS ON CHROMOSOME 1P
• WHOLE GENOME LINKAGE SCAN IN RA MULTICASE FAMILIES, USING 11,245 SNPS
• Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites
• ASSOCIATION OF RHEUMATOID ARTHRITIS (RA) TO PROGRAMMED CELL DEATH 2 (PDCD2), A POTENTIAL AUTOIMMUNE GENE
• CANDIDATE GENE ANALYSIS OF THE DISTAL EXTENDED MHC REGION IN RHEUMATOID ARTHRITIS
• FINE-MAPPING OF THE CHROMOSOME XP21-P11 REGION IN RHEUMATOID ARTHRITIS (RA)
• A replication study of the UK rheumatoid arthritis whole genome screen.
• EVIDENCE THAT A SECOND GENETIC EFFECT IN RA MAY EXIST DISTAL TO THAT ATTRIBUTED TO HLA-DRB1
• STRATIFICATION ANALYSIS REVEALS EVIDENCE FOR LINKAGE IN SUBSETS OF 378 RA ASP FAMILIES
• In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype
• Whole genome scan in a complex disease using 11,245 SNPs.
• Genetic Analysis of Candidate Genes for association with Abdominal Aortic Aneuryisms (AAA)
• A brief introduction to genetic epidemiology using Stata
• Sample size requirements for pilot randomised controlled trials with continuous outcomes: a simulation study
• Closing five Emergency Departments in England between 2009 and 2011: the closED controlled interrupted time-series analysis
• The DiPEP (Diagnosis of PE in Pregnancy) biomarker study: An observational cohort study augmented with additional cases to determine the diagnostic utility of biomarkers for suspected venous thromboembolism during pregnancy and puerperium
• The HubBLe Trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for symptomatic second- and third-degree haemorrhoids: a multicentre randomised controlled trial and health-economic evaluation.
• Sample size requirements for pilot randomised controlled trials with continuous outcomes: a simulation study.
• PLEASANT: Preventing and Lessening Exacerbations of Asthma in School-age children Associated with a New Term - a cluster randomised controlled trial and economic evaluation.
• Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial.
• Sample size requirements to estimate key design parameters from external pilot randomised controlled trials: a simulation study
• Non-invasive ventilation for weaning, avoiding reintubation after extubation and in the postoperative period: a meta-analysis.
• A Whole Genome by Association of Chronic Inflammatory Arthritis
• Data for Genetic Analysis Workshop (GAW) 15 Problem 2, genetic causes of rheumatoid arthritis and associated traits
• In adult onset myositis, the presence of interstitial lung disease (ILD) and myositis specific/associated antibodies (MSAs/MAAs) are governed by HLA class II haplotype, rather than by myositis subtype.