The University of Sheffield
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Neil Shephard

Publications

  • Derivation and validation of a risk adjustment model for predicting seven day mortality in emergency medical admissions: mixed prospective and retrospective cohort study
  • The HubBLe trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for haemorrhoids
  • The HubBLe trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for haemorrhoids.
  • A breast cancer risk haplotype in the caspase-8 gene
  • Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis
  • Genome wide association analysis of juvenile idiopathic arthritis (JIA) identifies a novel JIA susceptibility locus
  • Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs
  • Linkage analysis of cross-sectional and longitudinally derived phenotypic measures to identify loci influencing blood pressure
  • Association of rheumatoid arthritis (RA) to programmed cell death 2 (PDCD2), a potential autoimmune gene.
  • Angiotensinogen gene T235 variant: a marker for the development of persistent microalbuminuria in children and adolescents with type 1 diabetes mellitus
  • Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes
  • Identification of CASP8 haplotypes associated with breast cancer using haploConstructor
  • Multicentre study of CASP8 polymorphisms in breast cancer
  • A whole genome by association of chronic inflammatory arthritis
  • Association between osteopontin and human abdominal aortic aneurysm
  • Fine mapping of genes within the IDDM8 region in rheumatoid arthritis
  • Linkage analysis of rheumatoid arthritis in US and UK families reveals interactions between HLA--DRB1 and loci on chromosomes 6q and 16p
  • Will the real disease gene please stand up?
  • ANALYSIS OF COMBINED US-UK RA WGS IDENTIFIES A SUSCEPTIBILITY LOCUS ON CHROMOSOME 1P
  • WHOLE GENOME LINKAGE SCAN IN RA MULTICASE FAMILIES, USING 11,245 SNPS
  • Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites
  • ASSOCIATION OF RHEUMATOID ARTHRITIS (RA) TO PROGRAMMED CELL DEATH 2 (PDCD2), A POTENTIAL AUTOIMMUNE GENE
  • CANDIDATE GENE ANALYSIS OF THE DISTAL EXTENDED MHC REGION IN RHEUMATOID ARTHRITIS
  • FINE-MAPPING OF THE CHROMOSOME XP21-P11 REGION IN RHEUMATOID ARTHRITIS (RA)
  • A replication study of the UK rheumatoid arthritis whole genome screen.
  • EVIDENCE THAT A SECOND GENETIC EFFECT IN RA MAY EXIST DISTAL TO THAT ATTRIBUTED TO HLA-DRB1
  • STRATIFICATION ANALYSIS REVEALS EVIDENCE FOR LINKAGE IN SUBSETS OF 378 RA ASP FAMILIES
  • In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype
  • Whole genome scan in a complex disease using 11,245 SNPs.
  • Genetic Analysis of Candidate Genes for association with Abdominal Aortic Aneuryisms (AAA)
  • A brief introduction to genetic epidemiology using Stata
  • Sample size requirements for pilot randomised controlled trials with continuous outcomes: a simulation study
  • Closing five Emergency Departments in England between 2009 and 2011: the closED controlled interrupted time-series analysis
  • The DiPEP (Diagnosis of PE in Pregnancy) biomarker study: An observational cohort study augmented with additional cases to determine the diagnostic utility of biomarkers for suspected venous thromboembolism during pregnancy and puerperium
  • The HubBLe Trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for symptomatic second- and third-degree haemorrhoids: a multicentre randomised controlled trial and health-economic evaluation.
  • Sample size requirements for pilot randomised controlled trials with continuous outcomes: a simulation study.
  • PLEASANT: Preventing and Lessening Exacerbations of Asthma in School-age children Associated with a New Term - a cluster randomised controlled trial and economic evaluation.
  • Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial.
  • Sample size requirements to estimate key design parameters from external pilot randomised controlled trials: a simulation study
  • Non-invasive ventilation for weaning, avoiding reintubation after extubation and in the postoperative period: a meta-analysis.
  • A Whole Genome by Association of Chronic Inflammatory Arthritis
  • Data for Genetic Analysis Workshop (GAW) 15 Problem 2, genetic causes of rheumatoid arthritis and associated traits
  • In adult onset myositis, the presence of interstitial lung disease (ILD) and myositis specific/associated antibodies (MSAs/MAAs) are governed by HLA class II haplotype, rather than by myositis subtype.

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Co-workers & collaborators

Alice Pyne

Alice Pyne

Max Gamill

Max Gamill

Michael Pidd

Michael Pidd

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