Reviewing Response Adaptive Randomisation: Methods, Trials, and Resources

<p>FULL TITLE:</p> <p>A Methodological Review of Response Adaptive Randomisation Methods, Trials, and Statistical Resources</p> <p><br></p> <p>DESCRIPTION:</p> <p>This methodological review will be split into three work packages (WPs). The objectives of WP 1, 2, and 3 are, respectively, to identify statistical literature on response adaptive randomisation (RAR) methods applicable in clinical trial research, identify clinical trials that have used RAR methods, and identify RAR statistical implementation resources.</p> <p>We hope the findings will provide practical guidance on RAR methods to improve their uptake where appropriate and uncover key methodological gaps for future research.  </p> <p>This project does not require ethics approval.</p>