Organism: Human Embryonic (HEK) line samples: 3 x CRISPR Knockout HEK line cultures and 3x isogenic wild type HEK cell culturesArray: Clarion S array (Thermofisher)Experiment: whole genome gene expression profiling in MYT1L null HEK cell lines (generated by CRISPR) and 3 x isogenic wild type HEK cell lines. Protocol provided in "MYT1L mutations cause intellectual disability and variable obesity by dysregulating gene expression and development of the neuroendocrine hypothalamus" Published in PLoS Genetics, 13 (8). e1006957. ISSN 1553-7390 DOI: 10.1371/journal.pgen.1006957"C" files are from isogenic controls."21481" files are from MYT1L null cells